Empirical pathway analysis, without permutation
نویسندگان
چکیده
منابع مشابه
Empirical pathway analysis, without permutation
Resampling-based expression pathway analysis techniques have been shown to preserve type I error rates, in contrast to simple gene-list approaches that implicitly assume the independence of genes in ranked lists. However, resampling is intensive in computation time and memory requirements. We describe accurate analytic approximations to permutations of score statistics, including novel approach...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2013
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxt004